Metal-free C–H mercaptalization of benzothiazoles and benzoxazoles using 1,3-propanedithiol as thiol source
نویسندگان
چکیده
منابع مشابه
Direct arylation of benzothiazoles and benzoxazoles with aryl boronic acids.
Aryl-substituted benzothiazoles and benzoxazoles are an important class of heterocyclic compound and have shown a wide range of biological activities, such as antitumor, antiviral, and antimicrobial activities. In addition, these compounds have become essential building blocks for the synthesis of conjugated functional materials, such as industrial dyes and plant growth regulators. The conventi...
متن کاملCu-catalyzed in situ generation of thiol using xanthate as a thiol surrogate for the one-pot synthesis of benzothiazoles and benzothiophenes.
A new copper-catalyzed in situ generation of aryl thiolates strategy was successfully developed for the one-pot synthesis of substituted benzothiazoles from 2-iodoanilides using xanthate as a thiol precursor. A wide range of 2-iodoanilides with both electron-releasing and electron-withdrawing groups produced the corresponding benzothiazoles in good yields. Further, this one-pot protocol was suc...
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we used dbsa and nano-magnetic for the synthesis of amido alkylnaphtols.
15 صفحه اولAn easy and fast one-pot preparation of 2-thiomethyl and 2-thioacyl benzothiazoles, benzoxazoles, and benzimidazoles
Quaternary 2-thiomethylbenzazoles are important class of intermediates involved in the synthesis of symmetric and asymmetric monomethine cyanine dyes. In addition to, 2methylmercaptobenzothiazole, and 2methylmercaptobenzoxazole derivatives represent an essential group of compounds for the synthesis of cyanine dyes [1–3]. S-Alkylated heterocyclic derivatives are known as key compounds, finding a...
متن کاملMetal-free α-CH amination of ethers with hypervalent sulfonylimino-λ3-bromane that acts as an active nitrenoid.
Hypervalent N-triflylimino-λ(3)-bromane undergoes direct and regioselective α-C-H amination of ethers at room temperature under transition metal-free conditions. Kinetic results, substituent and deuterium isotope effects suggest an asynchronous concerted organonitrenoid transition state with some hydride transfer character, analogous to that for alkane C-H insertions.
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ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2019
ISSN: 1860-5397
DOI: 10.3762/bjoc.15.24